Curriculum vitae

Headshot

Michael J. Steinbaugh, Ph.D.
Research Fellow
Harvard Medical School
Joslin Diabetes Center
T. Keith Blackwell Lab
Islet Cell and Regenerative Biology
1 Joslin Place, Boston, MA 02215
mike@steinbaugh.com

Education and Training

9/12–pres.

Research Fellow
Islet Cell and Regenerative Biology, Joslin Diabetes Center
Department of Genetics, Harvard Medical School
Mentor: T. Keith Blackwell, M.D., Ph.D., Professor

5/12–8/12

Research Fellow
Department of Pathology, University of Michigan Medical School
Mentor: Richard A. Miller, M.D., Ph.D., Professor

9/05–4/12

Ph.D., Cellular and Molecular Biology
University of Michigan Medical School and Rackham Graduate School
Mentor: Richard A. Miller, M.D., Ph.D., Professor
Thesis: "Xenobiotic-metabolizing enzymes elevated in multiple mouse models of slow aging"

9/01–6/05

B.S., Microbiology, Immunology and Molecular Genetics
Minor in Spanish Language
University of California, Los Angeles

Additional

9/09–12/09

Financing Research Commercialization
Stephen M. Ross School of Business, University of Michigan

9/08

Molecular Biology of Aging
Marine Biological Laboratory, Woods Hole, MA

7/04–9/04

Research Intern
The Buck Institute for Research on Aging
Mentor: Lisa M. Ellerby, Ph.D., Associate Professor

9/03–6/05

Research Assistant
Department of Microbiology, Immunology and Molecular Genetics, UCLA
Mentor: Kenneth A. Bradley, Ph.D., Associate Professor
Thesis: "Identification of PA-competitive peptides via phage display"

Research Interests

Publications

6/18/15

T. Keith Blackwell, Michael J. Steinbaugh, John M. Hourihan, Collin Y. Ewald, and Meltem Isik. “SKN-1/Nrf, stress responses, and aging in Caenorhabditis elegans.” Invited review for upcoming Nrf2 special issue of Free Radic Biol Med.

2/20/14

John C. Yoon, Alvin J. Y. Ling, Meltem Isik, Dong-Young Donna Lee, Michael J. Steinbaugh, Laura M. Sack, Abigail N. Boduch, T. Keith Blackwell, David A. Sinclair, and Stephen J. Elledge. GLTSCR2/PICT1 links mitochondrial stress and Myc signaling. Proc Natl Acad Sci U S A 111:3781-6. doi:10.1073/pnas.1400705111; pmid:24556985

6/12/12

Michael J. Steinbaugh, Liou Y. Sun, Andrzej Bartke, and Richard A. Miller. Activation of genes involved in xenobiotic metabolism is a shared signature of mouse models with extended lifespan. Am J Physiol Endocrinol Metab 303:E488-95. doi:10.1152/ajpendo.00110.2012; pmid:22693205

9/26/09

Liou Y. Sun, Michael J. Steinbaugh, Michal M. Masternak, Andrzej Bartke, and Richard A. Miller. Fibroblasts from long-lived Snell and GHRKO mutant mice show diminished ERK phosphorylation but exaggerated induction of immediate early genes. Free Radic Biol Med 47:1753-61. doi:10.1016/j.freeradbiomed.2009.09.021; pmid:19786089

Presentations

International Meetings

3/23/15

8th International Keystone Symposium on Liver Metabolism and Nonalcoholic Fatty Liver Disease (NAFLD), Whistler, British Columbia, Canada

9/29/14

Molecular Genetics of Aging Symposium, Cold Spring Harbor Laboratory

6/27/13

19th International C. elegans Meeting, UCLA (selected talk)

7/25/10

10th International Symposium on Neurobiology and Neuroendocrinology of Aging, Bregenz, Austria. Exp Gerontol 46:210. doi:10.1016/j.exger.2010.11.019

2/1/10

Keystone Symposium on Molecular and Cellular Biology: New insights into healthspan and diseases of aging: From molecular to functional senescence, Tahoe City, CA, USA

Additional

4/30/15

Gene Expression and RNA Series (GEARS), Harvard

3/3/15

Boston Aging Data Club, Harvard

2/23/15

Harvard Genetics Retreat, Broad Institute

2/17/15

Joslin Research Seminar, Harvard

11/3/14

Joslin Research Retreat, Portsmouth, NH

3/26/14

Boston Area Worm Meeting, MIT

2/25/14

Harvard Genetics Retreat, Broad Institute

3/19/13

Salon on Aging, Harvard Stem Cell Institute

Research Support

6/14–5/16

Training grant in diabetes and metabolism
Ruth L. Kirschstein National Research Service Award (NRSA)
NIH / NIDDK; T32DK007260 (PI: Blackwell TK)

9/13–5/14

Regulation of SKN-1/Nrf by germline stem cells
NIH / NIA; R21AG043949 (PI: Blackwell TK)

12/12–5/13

Myra Reinhard Family Foundation Award (PI: Blackwell TK)

9/12–8/13

Regulation of SKN-1 functions by insulin-like signaling in C. elegans
NIH / NIGMS; R01GM062891 (PI: Blackwell TK)

4/11–8/12

Lifespan and mechanisms of stress resistance in GH/IGF mutants
NIH / NIA; P01AG031736 (PIs: Bartke A; Miller RA)

4/08–3/11

Biomedical research training in the biology of aging
Ruth L. Kirschstein National Research Service Award (NRSA)
NIH / NIA; T32AG000114 (PIs: Miller RA; Pletcher SD)

7/06–6/07

Cellular and Molecular Biology at Michigan
Ruth L. Kirschstein National Research Service Award (NRSA)
NIH / NIGMS; T32GM007315 (PI: Schwartz J)

9/05–6/06

Program in Biomedical Sciences, University of Michigan Medical School

Honors and Awards

2014–16

NIH NRSA T32 Training Grant at Joslin

2010

University of Michigan Rackham Conference Travel Grant to attend the 10th International Symposium on Neurobiology and Neuroendocrinology of Aging in Bregenz, Austria

2008

Ellison Medical Foundation Award to attend the Marine Biological Laboratory Molecular Biology of Aging course

2008–11

NIH NRSA T32 Training Grant at Michigan

2005

UCLA MIMG Departmental Honors

2005

UCLA College of Letters and Science Honors

2004–05

UCLA College of Letters and Science Dean’s Honors List

Teaching Experience

Mentoring

1/15–5/15

Reza Esmaillie (visiting from University of Cologne), Harvard

6/14–9/14

Edward J. Richardson (visiting from Boston College), Harvard

9/13–5/14

Rohan Goel, Harvard

9/11–4/12

Varol Ulas Ozkurede, Michigan

Courses

1/12/15

Instructor, Genetics 390, "Experimental approaches in genetic analysis", Harvard Medical School

1/9/14

Instructor, Genetics 390, "Experimental approaches in genetic analysis", Harvard Medical School

9/08–12/08

Teaching Assistant, DENT 525 001 "Cellular structure/function and pathogen biology", University of Michigan School of Dentistry

1/04–2/04

Student Mentor, CityLab, UCLA

9/03–12/03

Undergraduate Assistant, LS 194, "Teaching practicum in life science", UCLA

Skills

Genetics

Molecular Biology

Bioinformatics

Programming