Michael J. Steinbaugh, Ph.D.

Research Fellow at the Joslin Diabetes Center

Curriculum Vitae

Michael J. Steinbaugh, Ph.D.
Research Fellow
Harvard Medical School
Joslin Diabetes Center
T. Keith Blackwell Lab
Islet Cell and Regenerative Biology
1 Joslin Place, Boston, MA 02215
mike@steinbaugh.com

Education

9/05-4/12

Ph.D., Cellular and Molecular Biology
University of Michigan, Ann Arbor

9/01-6/05

B.S., Microbiology, Immunology and Molecular Genetics
Minor in Spanish Language
University of California, Los Angeles

Research Training

9/12-Pres.

Research Fellow
Islet Cell and Regenerative Biology, Joslin Diabetes Center
Department of Genetics, Harvard Medical School
Mentor: T. Keith Blackwell, M.D., Ph.D., Professor

5/12-8/12

Research Fellow
Department of Pathology, University of Michigan Medical School
Mentor: Richard A. Miller, M.D., Ph.D., Professor

9/05-4/12

Ph.D. Student
Cellular and Molecular Biology, Rackham Graduate School
University of Michigan Medical School
Mentor: Richard A. Miller, M.D., Ph.D., Professor
Thesis: "Xenobiotic-metabolizing enzymes elevated in multiple mouse models of slow aging"

7/04-9/04

Research Intern
The Buck Institute for Research on Aging
Mentor: Lisa M. Ellerby, Ph.D., Associate Professor

9/03-6/05

Research Assistant
Department of Microbiology, Immunology and Molecular Genetics, UCLA
Mentor: Kenneth A. Bradley, Ph.D., Associate Professor
Thesis: "Identification of PA-competitive peptides via phage display"

Courses

9/09-12/09

Financing Research Commercialization
Stephen M. Ross School of Business, University of Michigan

9/08

Molecular Biology of Aging
Marine Biological Laboratory, Woods Hole, MA

Publications

2/20/14

John C. Yoon, Alvin J. Y. Ling, Meltem Isik, Dong-Young Donna Lee, Michael J. Steinbaugh, Laura M. Sack, Abigail N. Boduch, T. Keith Blackwell, David A. Sinclair, Stephen J. Elledge. "GLTSCR2/PICT1 links mitochondrial stress and Myc signaling." Proc Natl Acad Sci U S A Epub ahead of print. doi:10.1073/pnas.1400705111; pmid:24556985

6/12/12

Michael J. Steinbaugh, Liou Y. Sun, Andrzej Bartke, and Richard A. Miller. "Activation of genes involved in xenobiotic metabolism is a shared signature of mouse models with extended lifespan." Am J Physiol Endocrinol Metab 303:E488-95. doi:10.1152/ajpendo.00110.2012; pmid:22693205

9/26/09

Liou Y. Sun, Michael J. Steinbaugh, Michal M. Masternak, Andrzej Bartke, and Richard A. Miller. "Fibroblasts from long-lived Snell and GHRKO mutant mice show diminished ERK phosphorylation but exaggerated induction of immediate early genes." Free Radic Biol Med 47:1753-61. doi:10.1016/j.freeradbiomed.2009.09.021; pmid:19786089

Presentations

Talks

4/18/14

Longwood Area Worm Meeting, Harvard

3/26/14

Boston Area Worm Meeting, MIT

6/27/13

19th International C. elegans Meeting, UCLA

3/19/13

Stem Cell Institute Salon on Aging, Harvard

4/20/12

Ph.D. thesis defense, CMB, University of Michigan

Posters

2/25/14

Harvard Genetics Retreat, Broad Institute

4/2/12

7th Annual Geriatrics Center Biogerontology Symposium, University of Michigan

11/3/11

10th Annual Pathology Research Symposium, University of Michigan

9/9/11

31st Annual CMB Symposium, University of Michigan

4/27/11

6th Annual Geriatrics Center Biogerontology Symposium, University of Michigan

9/10/10

30th Annual CMB Symposium, University of Michigan

7/25/10

10th International Symposium on Neurobiology and Neuroendocrinology of Aging, Bregenz, Austria. Exp Gerontol 46:210. doi:10.1016/j.exger.2010.11.019

4/20/10

5th Annual Geriatrics Center Biogerontology Symposium, University of Michigan

2/1/10

Keystone Symposia on Molecular and Cellular Biology: New insights into healthspan and diseases of aging: From molecular to functional senescence, Tahoe City, CA, USA

9/11/09

29th Annual CMB Symposium, University of Michigan

9/5/08

28th Annual CMB Symposium, University of Michigan

Research Support

6/14-5/15

Training grant in diabetes and metabolism
Ruth L. Kirschstein National Research Service Award (NRSA)
NIH/NIDDK; 5T32DK007260 (PI: Blackwell TK)

9/13-5/14

Regulation of SKN-1/Nrf by germline stem cells
NIH/NIA; 1R21AG043949 (PI: Blackwell TK)

12/12-5/13

Myra Reinhard Family Foundation Award (PI: Blackwell TK)

9/12-8/13

Regulation of SKN-1 functions by insulin-like signaling in C. elegans
NIH/NIGMS; 5R01GM062891 (PI: Blackwell TK)

4/11-8/12

Lifespan and mechanisms of stress resistance in GH/IGF mutants
NIH/NIA; 5P01AG031736 (PIs: Bartke A; Miller RA)

4/08-3/11

Biomedical research training in the biology of aging
Ruth L. Kirschstein National Research Service Award (NRSA)
NIH/NIA; 5T32AG000114 (PIs: Miller RA; Pletcher SD)

4/06-4/07

Cellular and Molecular Biology at Michigan
Ruth L. Kirschstein National Research Service Award (NRSA)
NIH/NIGMS; 5T32GM007315 (PI: Schwartz J)

9/05-3/06

Program in Biomedical Sciences, University of Michigan Medical School

Honors and Awards

2010

University of Michigan Rackham Conference Travel Grant to attend the 10th International Symposium on Neurobiology and Neuroendocrinology of Aging in Bregenz, Austria

2008

Ellison Medical Foundation Award to attend the Marine Biological Laboratory Molecular Biology of Aging course

2005

UCLA MIMG Departmental Honors

2005

UCLA College of Letters and Science Honors

2004-05

UCLA College of Letters and Science Dean’s Honors List

Teaching Experience

Mentoring

9/13-5/14

Edward J. Richardson, Boston College '16

9/13-5/14

Rohan Goel, Harvard University '15

9/11-4/12

Varol Ulas Ozkurede, Ph.D. Student, University of Michigan

Courses

1/9/14

Genetics 390, Genetics Boot Camp laboratory module, Harvard Medical School

9/08-12/08

Teaching Assistant, DENT 525 001 "Cellular structure/function and pathogen biology", University of Michigan School of Dentistry

1/04-2/04

CityLab student mentor, UCLA

9/03-12/03

Undergraduate assistant, LS 194 "Teaching practicum in life science", UCLA

Professional Societies

Skills

Genetics

Experienced with qRT-PCR, RNAi, and vector cloning. Currently learning RNA-seq and CRISPR-based gene editing. Have performed research with C. elegans and mouse models.

Molecular Biology

Skilled at performing protein immunoblots, cell fractionation/organelle enrichment, and live cell imaging of GFP-labeled proteins. Also familiar with flow cytometry, including live animal sorting of C. elegans with COPAS Biosort.

Programming

Familiar with HTML5, CSS3, PHP, MySQL, Apache, ASP, Galaxy, R, and the UNIX command line. Also experienced with numerous software applications, including Microsoft Office, Adobe Creative Cloud, GraphPad Prism, NIH ImageJ, ABI PRISM, and Zeiss ZEN.

Web design

Operated my own web design company during high school and college. Notable work included the launch version of GigaOm with Om Malik, now one of the most influential tech news sites on the Internet, and designs for writer and NYT/WSJ contributor Andy Kessler, consultant Louis Patler of The B.I.T. Group, consultant Robert Spears, comedian/actor Brody Stevens, and the food company Fresh Food Concepts.

Prepared on 7/22/14. PDF version and references available upon request.